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Elucidation of HIV-1 protease resistance by characterization of interaction kinetics between inhibitors and enzyme variants

BiochemistryProtein FoldingNatural SciencesMedicineHuman RetrovirusAntiviral Drug DevelopmentMolecular BiologyResistance Mutation (Virology)Hiv-1 Protease ResistanceProtein EngineeringStructure-function Enzyme KineticsInteraction KineticsAntiviral DrugHivProteomicsEnzyme VariantsDrug Resistance