Polymorphic oxidation of debrisoquine in lung cancer patients

POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN

A. Mahgoub, L. G. Dring, Jeffrey R. Idle et al. · The Lancet · 1977 · 1.2K citations

Pharmacy, Biochemistry, Pharmacology +6

Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

Frank J. Gonzalez, Radek C. Skodat, Shioko Kimura et al. · Nature · 1988 · 718 citations

Life Sciences, Genetics, Molecular Genetics +12

Aryl Hydrocarbon Hydroxylase Inducibility and Bronchogenic Carcinoma

Gottfried Kellermann, Charles R. Shaw, Mieke Luyten-Kellerman · New England Journal of Medicine · 1973 · 593 citations

Medicine, Biochemistry, Oncology +12

A family and population study of the genetic polymorphism of debrisoquine oxidation in a white British population.

David A. Evans, A. Mahgoub, T.P. Sloan et al. · Journal of Medical Genetics · 1980 · 540 citations · Full text

Life Sciences, Genetics, Pharmacology +17

Roles of cytochrome P-450 enzymes in chemical carcinogenesis and cancer chemotherapy.

F. Peter Guengerich · PubMed · 1988 · 461 citations

Medicine, Oncology, Pharmacology +16