Smac/Diablo Antagonizes Ubiquitin Ligase Activity of Inhibitor of Apoptosis Proteins

Smac, a Mitochondrial Protein that Promotes Cytochrome c–Dependent Caspase Activation by Eliminating IAP Inhibition

Chunying Du, Min Fang, Yucheng Li et al. · Cell · 2000 · 3.5K citations · Full text

Signal Transduction, Mitochondrial Function, Biochemistry +10

Identification of DIABLO, a Mammalian Protein that Promotes Apoptosis by Binding to and Antagonizing IAP Proteins

Anne M. Verhagen, Paul G. Ekert, Miha Pakusch et al. · Cell · 2000 · 2.3K citations · Full text

Protein Function, Autoimmune Disease, Apoptosis +9

X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen et al. · Nature · 1997 · 1.9K citations

Protein Function, Apoptosis, Autophagy +5

Ordering the Cytochrome c–initiated Caspase Cascade: Hierarchical Activation of Caspases-2, -3, -6, -7, -8, and -10 in a Caspase-9–dependent Manner

Elizabeth A. Slee, Mary T. Harte, Ruth M. Kluck et al. · The Journal of Cell Biology · 1999 · 1.9K citations · Full text

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

Natalie Roy · The EMBO Journal · 1997 · 1.3K citations · Full text

Protein Function, Signal Transduction, Specific Caspases +12