Convergence of alpha 7 nicotinic acetylcholine receptor-activated pathways for anti-apoptosis and anti-inflammation: Central role for JAK2 activation of STAT3 and NF-κB

Cytochrome c and dATP-Dependent Formation of Apaf-1/Caspase-9 Complex Initiates an Apoptotic Protease Cascade

Peng Li, Deepak Nijhawan, I. Imawati Budihardjo et al. · Cell · 1997 · 7.3K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation

Hong Wang, Man Yu, Mahendar Ochani et al. · Nature · 2002 · 3.2K citations

Life Sciences, Neurobiology, Neuroscience +11

Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

Hong Wang, Hong Liao, Mahendar Ochani et al. · Nature Medicine · 2004 · 1.2K citations

Veterinary Medicine, Immunology, Pharmacology +15

Stimulation of the vagus nerve attenuates macrophage activation by activating the Jak2-STAT3 signaling pathway

Wouter J. de Jonge, Esmerij P. van der Zanden, Frans Olivier The et al. · Nature Immunology · 2005 · 1.1K citations

Life Sciences, Immunology, Neuroscience +16

α7 Nicotinic Receptor Transduces Signals to Phosphatidylinositol 3-Kinase to Block A β-Amyloid-induced Neurotoxicity

Takeshi Kihara, Shun Shimohama, Hideyuki Sawada et al. · Journal of Biological Chemistry · 2001 · 413 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17