Concepedia

Interactive Association of Five Candidate Polymorphisms in Apelin/APJ Pathway with Coronary Artery Disease among Chinese Hypertensive Patients

Wei Jin, Xiuxiu Su, Min Xu, Yan Liu, Jingyi Shi, Lin Lu, Wenquan Niu

PLoS ONE · 2012 · 34 citations · 23 references

DOIFull text

Open access

Abstract

Our findings demonstrated a contributive role of low-penetrance haplotype in apelin gene on CAD in males, and more importantly, interactive effects of genetic defects in apelin/APJ pathway might confer a potential risk in Chinese hypertensive patients.

References

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