Premature cellular senescence induced by pyocyanin, a redox-active Pseudomonas aeruginosa toxin

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

The limited in vitro lifetime of human diploid cell strains

Leonard Hayflick · Experimental Cell Research · 1965 · 5.8K citations

Life Sciences, Cell Biology, Genetics +9

Senescence-associated β-galactosidase reflects an increase in lysosomal mass during replicative ageing of human endothelial cells

David J. Kurz, Stéphanie Decary, Ying Hong et al. · Journal of Cell Science · 2000 · 859 citations

Life Sciences, Biochemistry, Cell Biology +16

The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen.

Ian Y. R. Adamson, D. H. Bowden · PubMed · 1974 · 713 citations

Life Sciences, Cell Biology, Developmental Biology +16

Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.

Qian Chen, B N Ames · Proceedings of the National Academy of Sciences · 1994 · 631 citations

Life Sciences, Cell Biology, Molecular Biology +17