Nasal Administration: A Tool for Tomorrow's Systemic Administration of Drugs

Dominique Duchêne, Gilles Ponchel

Drug Development and Industrial Pharmacy · 1993 · 26 citations · 35 references

Concepts

Abstract

By its anatomy and physiology, due to the great amount of air treated there, the nasal route represents a very interesting possibility for the administration of products degraded in the gastro-intestinal tract or inhibited by the first hepatic pass. The nasal dosage forms most studied are bioadhesive hydrogels and microspheres, especially for the systemic administration of peptides.

References

35