A new enzyme involved in the control of the stereochemistry in the decalin formation during equisetin biosynthesis

Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis

Jonathan Kennedy, Karine Auclair, Steven G. Kendrew et al. · Science · 1999 · 659 citations

Engineering, Polyketide Synthase Activity, Molecular Biology +18

Navigating the Fungal Polyketide Chemical Space: From Genes to Molecules

Yit‐Heng Chooi, Yi Tang · The Journal of Organic Chemistry · 2012 · 256 citations

Engineering, Fungal Cell Biology, Molecular Biology +18

Accurate prediction of secondary metabolite gene clusters in filamentous fungi

Mikael Rørdam Andersen, Jakob Blæsbjerg Nielsen, Andreas Klitgaard et al. · Proceedings of the National Academy of Sciences · 2012 · 239 citations · Full text

Engineering, Molecular Biology, Secondary Metabolites +21

Lovastatin Nonaketide Synthase Catalyzes an Intramolecular Diels−Alder Reaction of a Substrate Analogue

Karine Auclair, Andrew Sutherland, Jonathan Kennedy et al. · Journal of the American Chemical Society · 2000 · 232 citations

Substrate Analogue, Bioorganic Chemistry, Biochemistry +7

Equisetin and a novel opposite stereochemical homolog phomasetin, two fungal metabolites as inhibitors of HIV-1 integrase

Sheo B. Singh, Deborah L. Zink, Michael Goetz et al. · Tetrahedron Letters · 1998 · 171 citations

Medicinal Chemistry, Hiv-1 Integrase, Antifungal Agent +8