Angewandte Chemie International Edition · 2000 · 36 citations · 10 references
Natural SciencesChemical EngineeringChemistryAnalytical ChemistryCatalysisChemical KineticsCatalyst CharacterizationCatalytic Reaction EngineeringCatalytic Reaction KineticsChemical SensorsChemical ThermodynamicsInfrared SpectroscopyCatalyst ScreeningCatalytic Reaction ThermodynamicsReaction Condition ScreeningThermistor ThermometryThermistorsThermochemistryThermocouple-based Sensing
An attractive alternative to IR thermography for the screening of combinatorial catalyst libraries: A multiplexed array of 96 thermistors has been used to probe the temperature changes associated with chemical and biochemical reactions (see schematic diagram). This new technique is more sensitive than IR thermography and can reliably detect temperature changes of 100 μK.
10
Rapid evolution of a protein in vitro by DNA shuffling
Willem P.C. Stemmer · Nature · 1994 · 1.9K citations
DNA shuffling of a family of genes from diverse species accelerates directed evolution
Andreas Crameri, Sun-Ai Raillard, Ericka Bermudez et al. · Nature · 1998 · 828 citations