PGC-1α and PGC-1β increase CrT expression and creatine uptake in myotubes via ERRα

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

Vamsi K. Mootha, Cecilia M. Lindgren, Karl‐Fredrik Eriksson et al. · Nature Genetics · 2003 · 10.6K citations

Life Sciences, Endocrinology, Molecular Biology +16

AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α

Sibylle Jäger, Christoph Handschin, Julie St‐Pierre et al. · Proceedings of the National Academy of Sciences · 2007 · 2.4K citations · Full text

Life Sciences, Biochemistry, Physiology +17

Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role of <i>PGC1</i> and <i>NRF1</i>

Mary‐Elizabeth Patti, Atul J. Butte, Sarah Crunkhorn et al. · Proceedings of the National Academy of Sciences · 2003 · 1.9K citations · Full text

Medicine, Molecular Genetics, Physiology +17

The Coactivator PGC-1 Cooperates with Peroxisome Proliferator-Activated Receptor α in Transcriptional Control of Nuclear Genes Encoding Mitochondrial Fatty Acid Oxidation Enzymes

Rick B. Vega, Janice M. Huss, Daniel P. Kelly · Molecular and Cellular Biology · 2000 · 1.2K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

Zoltàn Arany, ShiYin Foo, Yanhong Ma et al. · Nature · 2008 · 1.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14