Concepedia

Human fibroblast interferon gene lacks introns

Richard M. Lawn, John P. Adelman, Arthur E. Franke, Catherine M. Houck, Mitchell Gross, Richard C. Najarian, David V. Goeddel

Nucleic Acids Research · 1981 · 112 citations · 28 references

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Abstract

A recombinant lambda bacteriophage isolated from a human genome library contains the gene for fibroblast interferon (IFN-beta1). The DNA sequence of this gene is identical to the sequence of its mRNA and is devoid of introns.

References

28

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

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[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

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Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Geoffrey M. Wahl, Michael Stern, George R. Stark · Proceedings of the National Academy of Sciences · 1979 · 3.4K citations · Full text

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3′ Non-coding region sequences in eukaryotic messenger RNA

Nicholas Proudfoot, G.G. Brownlee · Nature · 1976 · 3K citations

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A general method for isolation of high molecular weight DNA from eukaryotes

Nikolaus Blin, Darrel W. Stafford · Nucleic Acids Research · 1976 · 2.8K citations · Full text

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