Caries Research · 2009 · 63 citations · 0 references
DentistryOral Health SciencesOral DiagnosisPreventive Dental MaterialsSalivary DiagnosticsFluoride TherapyFluoride UseSalivary FunctionConcentrationFluoride Dentifrice ConcentrationMouthrinse FormulationsSalivary Fluoride ConcentrationSalivary Fluoride LevelsSalivary Fluoride SecretionWhole Saliva Collection
The study consisted of eight experiments, divided into three series, aimed at investigating the effect on the salivary fluoride (F) concentration of three post-brushing regimes: (1) rinsing once or twice with water, (2) rinsing either with a slurry of the toothpaste foam and water or with an 0.05% NaF solution, or a single NaF mouthrinse with no prior brushing, and (3) chewing and drinking (‘eating’) for 2 min. Brushing was done with 1.5 g of an 0.32% NaF dentifrice. The concentration of F in whole saliva was determined in 15 subjects at various time points up to 45 min after completing each experimental procedure. Results showed that the initial (0 min post-brushing) F concentration in saliva decreased about 1-2 times after a single, and 4-5 times after a double post-brushing water-rinse, as compared with no rinsing at all (p < 0.001). Brushing followed by a mouthrinse with an 0.05% NaF solution elevated the F concentration more than brushing alone (p < 0.001). Rinsing with the slurry of toothpaste foam and water gave only a somewhat (but not significantly) lower concentration of F in saliva than just rinsing with the 0.05 % NaF solution. Eating immediatly after brushing reduced the salivary F level about 12-15 times (p < 0.001) compared with brushing alone. The conclusions from this study are therefore: (1) that both rinsing with water and eating immediately after toothbrushing accelerates the rate of F elimination in saliva, and (2) that mouthrinsing either with an 0.05% NaF solution or with the toothpaste foam-water slurry after brushing elevates the concentration of F in saliva for a prolonged period of time as compared with toothbrushing followed by a single or a double water-rinse.