Concepedia

Mode of action of hydroxychloroquine in RA—evidence of an inhibitory effect on toll-like receptor signaling

Diego Kyburz, Fabia Brentano, Steffen Gay

Nature Clinical Practice Rheumatology · 2006 · 135 citations · 7 references

DOI

Concepts

References

7

Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

Elizabeth A. Leadbetter, Ian R. Rifkin, Andreas M. Hohlbaum et al. · Nature · 2002 · 1.9K citations

, , +14

Treatment of Rheumatoid Arthritis with Methotrexate Alone, Sulfasalazine and Hydroxychloroquine, or a Combination of All Three Medications

James R. O’Dell, Claire E. Haire, N Erikson et al. · New England Journal of Medicine · 1996 · 655 citations · Full text

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RNA released from necrotic synovial fluid cells activates rheumatoid arthritis synovial fibroblasts via toll‐like receptor 3

Fabia Brentano, Olivier Schorr, Renate E. Gay et al. · Arthritis & Rheumatism · 2005 · 370 citations

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Presence of bacterial DNA and bacterial peptidoglycans in joints of patients with rheumatoid arthritis and other arthritides

Ineke M. van der Heijden, Bert Wilbrink, Ilja Tchetverikov et al. · Arthritis & Rheumatism · 2000 · 305 citations

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Chloroquine Interferes with Lipopolysaccharide-Induced TNF-α Gene Expression by a Nonlysosomotropic Mechanism

Stephen M. Weber, Stuart M. Levitz · The Journal of Immunology · 2000 · 130 citations · Full text

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