Native Functions of the Androgen Receptor Are Essential to Pathogenesis in a Drosophila Model of Spinobulbar Muscular Atrophy

Targeted gene expression as a means of altering cell fates and generating dominant phenotypes

Andrea H. Brand, Norbert Perrimon · Development · 1993 · 9.8K citations

Life Sciences, Developmental Biology, Genetics +17

Androgen receptor gene mutations in X-linked spinal and bulbar muscular atrophy

Albert R. La Spada, Elizabeth Wilson, Dennis B. Lubahn et al. · Nature · 1991 · 2.8K citations

Medicine, Genetics, Molecular Genetics +14

Huntingtin Acts in the Nucleus to Induce Apoptosis but Death Does Not Correlate with the Formation of Intranuclear Inclusions

Frédéric Saudou, Steven Finkbeiner, Didier Devys et al. · Cell · 1998 · 1.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

Udai Bhan Pandey, Zhiping Nie, Yakup Batlevi et al. · Nature · 2007 · 1.2K citations

Life Sciences, Cell Biology, Neuroscience +12

Ataxin-1 Nuclear Localization and Aggregation

Ivan A. Klement, Pamela J. Skinner, Michael D. Kaytor et al. · Cell · 1998 · 962 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8