Inhibition of RNA transcription: a biochemical mechanism of action against chronic lymphocytic leukemia cells by fludarabine

Action of 2',2'-difluorodeoxycytidine on DNA synthesis.

Peng Huang, Sherri Chubb, Larry W. Hertel et al. · PubMed · 1991 · 884 citations

Life Sciences, Genetics, Molecular Biology +11

Long-Term Follow-Up of Patients With Chronic Lymphocytic Leukemia (CLL) Receiving Fludarabine Regimens as Initial Therapy

Michael J. Keating, Susan O’Brien, Susan Lerner et al. · Blood · 1998 · 422 citations

Medicine, Oncology, Chemotherapy +10

Guidelines for clinical protocols for chronic lymphocytic leukemia: Recommendations of the national cancer institute‐sponsored working group

Bruce D. Cheson, John M. Bennett, Michael R. Grever et al. · American Journal of Hematology · 1988 · 407 citations

Medicine, Hematology, Immunology +16

Induction of apoptotic cell death in chronic lymphocytic leukemia by 2- chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine

L. E. Robertson, Sherri Chubb, RE Meyn et al. · Blood · 1993 · 275 citations · Full text

Life Sciences, Cell Biology, Oncology +14

Drug-induced apoptosis in B-cell chronic lymphocytic leukemia: relationship between p53 gene mutation and bcl-2/bax proteins in drug resistance.

Alexander S. Thomas, Soumaya El Rouby, John C. Reed et al. · PubMed · 1996 · 273 citations

Medicine, Cancer Biology, Oncology +14