RNAi targeting µ-calpain increases neuron survival and preserves hippocampal function after global brain ischemia

Recombinant adeno-associated virus for muscle directed gene therapy

Krishna J. Fisher, Karin Jooss, J. M. Alston et al. · Nature Medicine · 1997 · 654 citations

Medicine, Biotechnology, Molecular Genetics +11

Cleavage of the Plasma Membrane Na+/Ca2+ Exchanger in Excitotoxicity

Daniele Bano, Kenneth W. Young, Christopher J. Guérin et al. · Cell · 2005 · 531 citations · Full text

Life Sciences, Biochemistry, Cell Biology +11

Calpain I Induces Cleavage and Release of Apoptosis-inducing Factor from Isolated Mitochondria

Brian M. Polster, Gorka Basáñez, Aitor Etxebarria et al. · Journal of Biological Chemistry · 2004 · 430 citations · Full text

Life Sciences, Biochemistry, Neuroscience +17

Inhibition of proteolysis protects hippocampal neurons from ischemia.

K S Lee, Stefan L. Frank, Peter W. Vanderklish et al. · Proceedings of the National Academy of Sciences · 1991 · 364 citations

Medicine, Neurobiology, Neuroscience +17

Immunolocalization of calpain I-mediated spectrin degradation to vulnerable neurons in the ischemic gerbil brain

JM Roberts-Lewis, MJ Savage, VR Marcy et al. · Journal of Neuroscience · 1994 · 320 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15