Multiequilibrium binding of a spin-labeled local anesthetic in phosphatidylcholine bilayers

Lipoid pH indicators as probes of electrical potential and polarity in micelles

Marta Fernández, Peter Fromherz · The Journal of Physical Chemistry · 1977 · 577 citations

Natural Sciences, Biochemistry, Chemistry +13

Effects of local anesthetics on membrane properties I. Changes in the fluidity of phospholipid bilayers

D. Papahadjopoulos, Kenneth A. Jacobson, George Poste et al. · Biochimica et Biophysica Acta (BBA) - Biomembranes · 1975 · 335 citations

Natural Sciences, Biophysics, Pharmacology +16

A Unitary Theory of Anesthesia Based on Lateral Phase Separations in Nerve Membranes

James R. Trudell · Anesthesiology · 1977 · 235 citations · Full text

Natural Sciences, Anesthesiology, Pharmacology +17

THE SITE OF ACTION AND ACTIVE FORM OF LOCAL ANESTHETICS. I. THEORY AND pH EXPERIMENTS WITH TERTIARY COMPOUNDS

Toshio Narahashi, D. T. Frazier, Minoru Yamada · Journal of Pharmacology and Experimental Therapeutics · 1970 · 220 citations

Medicine, Neurobiology, Pharmacology +13

Molecular details of anesthetic-lipid interaction as seen by deuterium and phosphorus-31 nuclear magnetic resonance

Yvan Boulanger, Shirley Schreier, Ian C. P. Smith · Biochemistry · 1981 · 198 citations

Life Sciences, Biochemistry, Chemistry +13