The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to all-trans-retinoic acid

Publication | Closed Access

DOI

Citations

References

1994

Year

Georg Tzimas, Heinrich Bürgin, Michael D. Collins, Hans Hummler, Heinz Nau

Archives of Toxicology

All-trans-retinoic AcidXenotransplantationDevelopmental BiologyHigh SensitivityMedicinePhotocarcinogenesis13-Cis-retinoic AcidEndocrinologyPharmacologyEmbryology