Concepedia

The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to all-trans-retinoic acid

Georg Tzimas, Heinrich Bürgin, Michael D. Collins, Hans Hummler, Heinz Nau

Archives of Toxicology · 1994 · 49 citations · 39 references

DOI

Concepts

References

39

Retinoic Acid Embryopathy

Edward J. Lammer, Diane T. Chen, Richard M. Hoar et al. · New England Journal of Medicine · 1985 · 1.9K citations

, , +14

A Note on the Staining of the Skeleton of Cleared Specimens with Alizarin Red S

Alden B. Dawson · Stain Technology · 1926 · 1K citations

, , +10

Retinoids and their receptors in differentiation, embryogenesis, and neoplasia

Luigi M. De Luca · The FASEB Journal · 1991 · 851 citations

, , +12

Local application of retinoic acid to the limb bond mimics the action of the polarizing region

Cheryll Tickle, Bruce Alberts, Lewis Wolpert et al. · Nature · 1982 · 666 citations

, , +13

Retinoic acid receptors and cellular retinoid binding proteins: I. A systematic study of their differential pattern of transcription during mouse organogenesis

Pascal Dollé, Esther Ruberte, Pierre Leroy et al. · Development · 1990 · 580 citations

, , +16