Insulin-sensitizing effect of rosiglitazone (BRL-49653) by regulation of glucose transporters in muscle and fat of Zucker rats

The Organization, Promoter Analysis, and Expression of the Human PPARγ Gene

Lluís Fajas, Didier Auboeuf, Eric Raspé et al. · Journal of Biological Chemistry · 1997 · 1.2K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +10

Improvement in Glucose Tolerance and Insulin Resistance in Obese Subjects Treated with Troglitazone

John J. Nolan, Bernhard Ludvik, P. Beerdsen et al. · New England Journal of Medicine · 1994 · 935 citations · Full text

Medicine, Endocrinology, Pharmacology +15

Peroxisome proliferator-activated receptor gene expression in human tissues. Effects of obesity, weight loss, and regulation by insulin and glucocorticoids.

Antonio Vidal‐Puig, Robert V. Considine, Mercedes Jimenez‐Liñan et al. · Journal of Clinical Investigation · 1997 · 789 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +16

Evidence for 5′AMP-Activated Protein Kinase Mediation of the Effect of Muscle Contraction on Glucose Transport

Tatsuya Hayashi, Michael F. Hirshman, E. J. Kurth et al. · Diabetes · 1998 · 741 citations

Life Sciences, Biochemistry, Physiology +15

Structural organization of mouse peroxisome proliferator-activated receptor gamma (mPPAR gamma) gene: alternative promoter use and different splicing yield two mPPAR gamma isoforms.

Yi Zhu, Chao Qi, Julie R. Korenberg et al. · Proceedings of the National Academy of Sciences · 1995 · 646 citations · Full text

Medicine, Molecular Biology, Molecular Genetics +15