Synthesis and structure–activity relationships of novel arylalkyl 4-benzyl piperazine derivatives as σ site selective ligands

ELECTROPHYSIOLOGY OF HIPPOCAMPAL NEURONS: II. AFTER-POTENTIALS AND REPETITIVE FIRING

Eric R. Kandel, W. A. Spencer · Journal of Neurophysiology · 1961 · 688 citations

Life Sciences, Neurobiology, Neuroscience +13

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin

Daniël Hoyer, G. Engel, Hans O. Kalkman · European Journal of Pharmacology · 1985 · 577 citations

Life Sciences, Neuroscience, Pharmacology +13

Specific in vitro and in vivo binding of 3H-raclopride a potent substituted benzamide drug with high affinity for dopamine D-2 receptors in the rat brain

Christer Köhler, Håkan Hall, Sven Ove Ögren et al. · Biochemical Pharmacology · 1985 · 506 citations

Medicine, Neuroscience, Pharmacology +12

N-methyl-D-aspartate-induced neuronal activation is selectively modulated by σ receptors

François P. Monnet, Guy Debonnel, Jean‐Louis Junien et al. · European Journal of Pharmacology · 1990 · 230 citations

Life Sciences, Neurobiology, Neuroscience +12

Stereotyped behaviour patterns and hyperactivity induced by amphetamine and apomorphine after discrete 6-hydroxydopamine lesions of extrapyramidal and mesolimbic nuclei

B. Costall, C. D. Marsden, Robert J. Naylor et al. · Brain Research · 1977 · 227 citations

Life Sciences, Neuroscience, Pharmacology +16