Concepedia

Total Synthesis of (−)-Corilagin

Hidetoshi Yamada, Kohei Nagao, Kazutoyo Dokei, Yusuke Kasai, Naoki Michihata

Journal of the American Chemical Society · 2008 · 97 citations · 17 references

DOI

Concepts

Abstract

The synthesis of corilagin was achieved by the integration of the development of the oxidative coupling of the symmetrically protected gallates and the temporarily ring-opened synthetic route for the 3,6-hexahydroxydiphenoyl (HHDP) bridge. This is the first total synthesis of the 1C4/B-ellagitannins, which contain ring-flipped glucose.

References

17

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