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A computer program for writing the steady-state rate equation for a multisubstrate enzymic reaction
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1969
Year
EngineeringEnzyme SpeciesSteady-state Rate EquationMetabolic ModelFortran Iv LanguageBiosynthesisBioenergeticsBiochemical EngineeringMetabolic EngineeringReaction IntermediateStructure-function Enzyme KineticsMultisubstrate Enzymic ReactionBiochemistryBiocatalysisComputer ProgramDeterminant ProcedureBiomolecular EngineeringCellular EnzymologyNatural SciencesEnzyme CatalysisProcess ControlSynthetic BiologyMicrobiologyReaction ProcessChemical Kinetics
The determinant procedure for deriving the rate equation for an enzymic mechanism has been converted into Fortran IV language for use with a digital computer. The distribution equations for three to nine enzyme species, which may interact along all possible pathways, can be determined readily, limited only by the size of the memory capacity of the computer employed. The method permits several mechanisms to be analyzed in a matter of a few minutes.