Vox Sanguinis · 1971 · 21 citations · 7 references
HistocompatibilityGeneticsImmunologyImmunodominanceMolecular GeneticsImmunotherapyImmune-related Gene PolymorphismImmunogeneticsAntigenic DeterminantMolecular DiagnosticsAutoimmune DiseaseHuman Leukocyte AntigenAutoimmunityGenetic VariationInborn Error Of ImmunityNew Antigenic DeterminantGm AllotypesHuman Igg3 ImmunoglobulinsHla TypingImmunoglobulin EMedicine
Abstract. A new antigenic determinant was found which is present on proteins of the main IgG3 allotypes, Gm(g) and Gm(b), but absent from IgG3 proteins carrying Gm(s). It was shown to be a genetical marker in family studies. The antiserum detecting this specificity is similar to antisera of ‘long specificity’, which term is used in HL‐A serology. The antigenic determinant offers a link for the generation sequence of Gm allotypes during evolution.
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Gm(s) and Gm(t): Genetic Determinants of Human γ‐Globulin*
L. Mårtensson, Erna van Loghem, Hideo Matsumoto et al. · Vox Sanguinis · 1966 · 54 citations