Concepedia

Validation of the comet-X assay as a pharmacodynamic assay for measuring DNA cross-linking produced by the novel anticancer agent RH1 during a phase I clinical trial

Sarah Danson, Malcolm Ranson, O. Denneny, Jeffrey L. Cummings, Timothy H. Ward

Cancer Chemotherapy and Pharmacology · 2007 · 22 citations · 27 references

DOI

Concepts

References

27

Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

Raymond R. Tice, Eva Agurell, Diana Anderson et al. · Environmental and Molecular Mutagenesis · 2000 · 4.8K citations

, , +17

Microelectrophoretic study of radiation-induced DNA damages in individual mammalian cells

O. Östling, Karl J. Johanson · Biochemical and Biophysical Research Communications · 1984 · 1.7K citations

, , +15

Bioanalytical Method Validation—A Revisit with a Decade of Progress

Vinod P. Shah, Kamal K. Midha, John W. A. Findlay et al. · Pharmaceutical Research · 2000 · 1.6K citations

, , +11

Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the "Comet" Assay

Peggy L. Olive, Judit P. Banáth, Ralph E. Durand et al. · Radiation Research · 1990 · 1.1K citations

, , +14

Heterogeneity in Radiation-Induced DNA Damage and Repair in Tumor and Normal Cells Measured Using the “Comet” Assay

Peggy L. Olive, Judit P. Banáth, Ralph E. Durand · Radiation Research · 2012 · 1K citations

, , +17