Total Hydroperoxide and Biological Antioxidant Potentials in a Neonatal Sepsis Model

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

Albena T. Dinkova‐Kostova, W. David Holtzclaw, Robert N. Cole et al. · Proceedings of the National Academy of Sciences · 2002 · 1.9K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Interleukin-6 (IL-6) as an anti-inflammatory cytokine: induction of circulating IL-1 receptor antagonist and soluble tumor necrosis factor receptor p55

Herbert Tilg, Elizabeth Trehu, MB Atkins et al. · Blood · 1994 · 794 citations · Full text

Life Sciences, Immunology, Pharmacology +14

Effects of Melatonin Treatment in Septic Newborns

Eloisa Gitto, R.J. Reiter, Salvatore Cuzzocrea et al. · Pediatric Research · 2001 · 509 citations · Full text

Medicine, Child Health, Pediatrics +14

Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction

Helen F. Goode, Hugh Cowley, B. E. Walker et al. · Critical Care Medicine · 1995 · 474 citations

Veterinary Medicine, Toxicology, Nutritional Support In Critical Care +15

Lipopolysaccharide Induces Rac1-dependent Reactive Oxygen Species Formation and Coordinates Tumor Necrosis Factor-α Secretion through IKK Regulation of NF-κB

Salih Şanlıoğlu, Carl M. Williams, Lobelia Samavati et al. · Journal of Biological Chemistry · 2001 · 392 citations · Full text

Life Sciences, Cell Biology, Immunology +15