The Laryngoscope · 2007 · 32 citations · 11 references
MedicineOtolaryngologySurgeryOtolaryngologic SurgeryPulmonologySleep MedicineAirway ObstructionAirway SurgerySleep Apnea CareSleep SurgerySleep-disordered BreathingSleep-related Breathing DisordersAirway Pressure MonitoringSleep Apnea MonitoringSleep Apnea SyndromeSleep-related Breathing MonitoringSnoring ReductionSurgical Management Of Snoring
OBJECTIVES: Sleep-related breathing disorders (SRBD) that cannot be treated conservatively are commonly treated using uvulopalatopharyngoplasty, although success rates are generally less than 70%. The purpose of this study was to assess a plasma-mediated radiofrequency (RF)-based coblation assisted upper airway procedure (CAUP) to treat SRBD patients determined to have obstruction localized to the upper (mid)-pharyngeal region. STUDY DESIGN: Prospective case series (n = 40). METHODS: Six patients had socially bothersome snoring, and 34 patients had mild to moderate sleep apnea (apnea/hypopnea index [AHI] <20), with the primary level of obstruction (>50%) within the upper pharyngeal region as determined using whole night recordings, including airway pressure fluctuation monitoring (ApneaGraph, MRA-Medical Ltd, Gloucestershire, UK). CAUP consisted of making a lateral palatal incision, ablating three upward channels on each side of the midline (fan-shaped) into the soft palate using a plasma mediated RF-based device (ArthroCare Corporation, Austin, TX), and performing a partial uvulectomy. Clinical outcomes included the Epworth Sleepiness Scale (ESS), partner rating of snoring using a visual analogue scale (VAS), and night-time apnea and hypopnea events (AHI, hypopnea index [HI], apnea index [AI]). RESULTS: Patients were 28 to 68 (46 +/- 12) years old; 28 (70%) were male. Preoperatively, clinical assessment scores (median +/- interquartile range) were as follows: ESS (11.0 +/- 3.0), VAS (8.15 +/- 1.00), AHI (9.58 +/- 5.58), HI (9.00 +/- 5.29), AI (0.333 +/- 0.625). After CAUP, no postoperative scarring, fibrosis, or any other clinically significant side effects were observed. Postoperatively (9.1 +/- 1.5; 7-15 mo), ESS (4.0 +/- 1.0), VAS (2.70 +/- 1.38), AHI (3.75 +/- 2.92), HI (3.58 +/- 2.50), and AI (0.167 +/- 0.167) were significantly improved (P < .001). CONCLUSION: CAUP preceded by site-specific obstruction diagnosis using pressure recording is a well-tolerated outpatient treatment that is well suited for treating SRBD.
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Terry Young, Linda Evans, Laurel Finn et al. · SLEEP · 1997 · 1.8K citations · Full text
Investigating the Relationship Between Stroke and Obstructive Sleep Apnea
Mark Eric Dyken, Virend K. Somers, Thoru Yamada et al. · Stroke · 1996 · 579 citations
Surgery and Obstructive Sleep Apnea: Long‐Term Clinical Outcomes
Robert W. Riley, Nelson B. Powell, Kasey K. Li et al. · Otolaryngology · 2000 · 168 citations