The Nephron journals/Nephron journals · 2008 · 61 citations · 0 references
MedicineNephrologyPhysiologyDialysisHemodialysisRenal Replacement TherapyAutonomic DisordersAutonomic Nervous System DisordersAutonomic Nervous System TestingChronic HemodialysisChronic Kidney DiseaseRenal DiseaseAutonomic Cardiovascular ControlAutonomic Cardiovascular TestingAutonomic Nervous System DysfunctionCardiovascular Autonomic ControlCardiovascular Autonomic Reflex TestingChronic Renal InsufficiencySympathetic Function TestingSympathetic Responding
Autonomic function was assessed in 67 patients with chronic renal failure using a standardized battery of five cardiovascular reflex tests. The results showed that 38 (65%) had early or definite parasympathetic abnormalities, while 14 (24%) had additional sympathetic damage. There were no significant differences between those treated conservatively (n = 19), those on continuous ambulatory peritoneal dialysis (n = 8) and those on intermittent haemodialysis (n = 40). Cardiovascular autonomic damage is widespread among patients with chronic renal failure, however treated, and may have a number of clinical sequelae.