Concepedia

Targeting cancer stem cells for more effective therapies: Taking out cancer's locomotive engine

Raymond J. Winquist, Diane M. Boucher, Mark Wood, Brinley F. Furey

Biochemical Pharmacology · 2009 · 45 citations · 53 references

Concepts

MedicineCancer BiologyOncologyMolecular OncologyStem Cell BiologyTumor MicroenvironmentCancer Stem Cell BiologyCancer Stem Cell MaintenanceCancer Stem Cell NicheCancer Stem CellsCell-based TherapiesTargeted Cancer TherapyCancer Stem Cell Niche InteractionsCancer Stem Cell NichesCancer Stem Cell ProliferationCancer Stem Cell Signaling PathwaysCancer Stem Cell SurvivalCancer Stem Cell TargetingCancer Stem-like Cells

References

53

Prospective identification of tumorigenic breast cancer cells

Muhammad Al‐Hajj, Max S. Wicha, Adalberto Benito‐Hernández et al. · Proceedings of the National Academy of Sciences · 2003 · 10.4K citations · Full text

Medicine, Cell Biology, Oncology +11

Identification of human brain tumour initiating cells

Sheila K. Singh, Cynthia Hawkins, Ian D. Clarke et al. · Nature · 2004 · 7.4K citations

Medicine, Cancer Biology, Oncology +11

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

Medicine, Hematology, Oncology +14

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Shideng Bao, Qiulian Wu, Roger E. McLendon et al. · Nature · 2006 · 6.4K citations

Medicine, Cancer Biology, Oncology +16

A Direct Measurement of the Radiation Sensitivity of Normal Mouse Bone Marrow Cells<sup>1</sup>

J. E. Till, E. A. McCulloch · Radiation Research · 2010 · 4.1K citations · Full text

Medicine, Biophysics, Cell Biology +17