VEGF‐Mediated Elevated Intracellular Calcium and Angiogenesis in Human Microvascular Endothelial Cells <i>In Vitro</i> are Inhibited by Dominant Negative TRPC6

Abstract

TRPC6 is an obligatory component of cation channels required for the VEGF-mediated increase in cytosolic calcium and subsequent downstream signaling that leads to processes associated with angiogenesis.