Bivalent inhibition of β-Tryptase: distance scan of neighboring subunits by dibasic inhibitors

Validation of the general purpose tripos 5.2 force field

Matthew Clark, Richard D. Cramer, N. Van Opdenbosch · Journal of Computational Chemistry · 1989 · 2.8K citations

Engineering, Computational Chemistry, Verification And Validation +18

Human β-tryptase is a ring-like tetramer with active sites facing a central pore

Pedro José Barbosa Pereira, Andreas Bergner, Sandra Macedo‐Ribeiro et al. · Nature · 1998 · 296 citations

Protein Secretion, Signal Transduction, Molecular Physiology +11

Maximally diagonal force constants in dependent angle-bending coordinates. II. Implications for the design of empirical force fields

Thomas A. Halgren · Journal of the American Chemical Society · 1990 · 166 citations

Geometric Modeling, Altmetrics, Engineering +15

The structure of the human βII-tryptase tetramer: Fo(u)r better or worse

Christian P. Sommerhoff, Wolfram Bode, Pedro José Barbosa Pereira et al. · Proceedings of the National Academy of Sciences · 1999 · 77 citations

Protein Chemistry, Molecular Pharmacology, Protein Function +15

Mast Cell Tryptases and Airway Remodeling

CHRISTIAN P. SOMMERHOFF · American Journal of Respiratory and Critical Care Medicine · 2001 · 73 citations