Journal of Computational and Graphical Statistics · 2014 · 240 citations · 68 references
Public HealthBiostatisticsCausal InferenceSpatial Data AnalysisSpatial StatisticsGeneralized Linear ModelsLongitudinal Data AnalysisMixed Model AnalysisMixed-effects ModelsNonlinear Mixed-effects ModelingSpatial ConfoundingFunctional Response ModelsGeneralized Linear Mixed-effects ModelsLinear Mixed ModelsLongitudinal Data ModelingNonlinear Covariate EffectsNonlinear EffectsResponse CovariatesSpatial Random Effects Models
We propose an extensive framework for additive regression models for correlated functional responses, allowing for multiple partially nested or crossed functional random effects with flexible correlation structures for, e.g., spatial, temporal, or longitudinal functional data. Additionally, our framework includes linear and nonlinear effects of functional and scalar covariates that may vary smoothly over the index of the functional response. It accommodates densely or sparsely observed functional responses and predictors which may be observed with additional error and includes both spline-based and functional principal component-based terms. Estimation and inference in this framework is based on standard additive mixed models, allowing us to take advantage of established methods and robust, flexible algorithms. We provide easy-to-use open source software in the pffr() function for the R-package refund. Simulations show that the proposed method recovers relevant effects reliably, handles small sample sizes well and also scales to larger data sets. Applications with spatially and longitudinally observed functional data demonstrate the flexibility in modeling and interpretability of results of our approach.
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R: A Language and Environment for Statistical Computing
R Core Team · 2000 · 353K citations · Full text
Natural Sciences, Computer Science, Statistical Computing +10
In vivo fiber tractography using DT-MRI data
Peter J. Basser, Sinisa Pajevic, Carlo Pierpaoli et al. · Magnetic Resonance in Medicine · 2000 · 3.1K citations
Medicine, Anatomy, Neuroscience +17