Methyl 2-amino-4-(3-fluorophenyl)-4<i>H</i>-benzo[<i>h</i>]chromene-3-carboxylate methanol solvate

Abstract

The title compound, C 21 H 16 FNO 3 ·CH 3 OH, was synthesized by the reaction of 1-naphthol with methyl cyanoacetate and 3-fluorobenzaldehyde in methanol under microwave irradiation. The pyran rings of the two independent molecules in the asymmetric unit adopt boat conformations. The crystal packing is stabilized by intermolecular N—H...O, O—H...O and C—H...π interactions.