Journal of the American Chemical Society · 2006 · 72 citations · 5 references
EngineeringChemical EngineeringMaterials ScienceDrug DeliveryMagnetic MaterialsMicrofabricationMagnetic NanomaterialsMicrofluidic Device FabricationMicrofluidic DevicesMicrofluidic SystemsMicrofluidicsMicroscale Drug Delivery SystemsEncapsulationMagnetic Drug ReleaseMagnetic Field - Responsive MaterialsMagnetic Field-responsive ReleaseMagnetic-responsive MaterialsMagnetically Triggered Drug DeliveryNanostructured Magnetic MaterialsPorosity
In this communication we describe a new chemical encapsulation and release platform using 3D microfabricated nanoliter scale containers with controlled porosity. The containers can be fabricated of magnetic materials that allow them to be remotely guided using magnetic fields. The favorable attributes of the containers that include a versatile highly parallel fabrication process, precisely engineered porosity, isotropic/anisotropic chemical release profiles, and remote magnetic guiding provide an attractive platform for engineering spatially controlled chemical reactions in microfluidic systems.
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