Exploring the quantitative relationship between the level of MDR1 transcript, protein and function using digoxin as a marker of MDR1-dependent drug efflux activity

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

Medicine, Molecular Genetics, Pharmacology +15

A genomic view of alternative splicing

Barmak Modrek, Christopher Lee · Nature Genetics · 2002 · 1.3K citations

Life Sciences, Genetics, Molecular Biology +11

The Human ATP-Binding Cassette (ABC) Transporter Superfamily

Michael Dean · Genome Research · 2001 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +17

The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin

Bernd Greiner, Michel Eichelbaum, Péter Fritz et al. · Journal of Clinical Investigation · 1999 · 920 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +9

Organic anion-transporting polypeptide B (OATP-B) and its functional comparison with three other OATPs of human liver

Gerd A. Kullak‐Ublick, Manfred G. Ismair, Bruno Stieger et al. · Gastroenterology · 2001 · 724 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8