Concepedia

Direct Reductive Amination of Aldehydes and Ketones Using Phenylsilane:  Catalysis by Dibutyltin Dichloride

Richard L. Apodaca, Wei Xiao

Organic Letters · 2001 · 162 citations · 17 references

DOI

Concepts

Abstract

A procedure for direct reductive amination of aldehydes and ketones was developed which uses phenylsilane as a stoichiometric reductant and dibutyltin dichloride as a catalyst. Suitable amines included anilines and dialkylamines but not monoalkylamines.

References

17

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