Concepedia

A supramolecular hydrogel as a carrier to deliver microRNA into the encapsulated cells

Jinbo Li, Romain Kooger, Mingtao He, Xiao Xiao, Li Min Zheng, Yan Zhang

Chemical Communications · 2014 · 38 citations · 35 references

DOI

Abstract

A supramolecular hydrogel formed by dipeptide Gly-Ala linked with biphenyl-substituted tetrazole serves not only as a 3D matrix for live cells, but also as a carrier to deliver microRNA into the encapsulated cells.

References

35

MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis

Wei-Chih Tsai, Sheng‐Da Hsu, Chu-Sui Hsu et al. · Journal of Clinical Investigation · 2012 · 795 citations · Full text

, , +22

Enzymatic Hydrogelation of Small Molecules

Zhimou Yang, Gaolin Liang, Bing Xu · Accounts of Chemical Research · 2008 · 655 citations

Encapsulation of curcumin in self-assembling peptide hydrogels as injectable drug delivery vehicles

Ayşegül Altunbaş, Seung Joon Lee, Sigrid A. Rajasekaran et al. · Biomaterials · 2011 · 493 citations · Full text

, , +8

First microRNA mimic enters clinic

Aaron Bouchie · Nature Biotechnology · 2013 · 469 citations · Full text

, , +5

Supramolecular Hydrogels Respond to Ligand−Receptor Interaction

Yan Zhang, Hongwei Gu, Zhimou Yang et al. · Journal of the American Chemical Society · 2003 · 455 citations