Modulation of Immune Signaling, Bacterial Clearance, and Corneal Integrity by Toll-like Receptors during<i>Streptococcus pneumoniae</i>Keratitis

Abstract

TLR2 and TLR4 are involved in the response to pneumococcal keratitis and TLR2 may aid in bacterial clearance by recruitment of neutrophils to the cornea, whereas TLR4 may be necessary to modulate the immune response to limit cellular damage.