Ionizing Radiation Shifts the PAI-1/ID-1 Balance and Activates Notch Signaling in Endothelial Cells

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

Anne Joutel, Christophe Corpechot, Anne Ducros et al. · Nature · 1996 · 2K citations

Neurobiology Of Disease, Notch3 Mutations, Mendelian Disorder +8

Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis

Mats Hellström, Li-Kun Phng, Jennifer J. Hofmann et al. · Nature · 2007 · 1.7K citations

Lineage Plasticity, Signal Transduction, Developmental Biology +9

SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7

Gareth J. Inman, Francisco José Nicolás, James F. Callahan et al. · Molecular Pharmacology · 2002 · 1.6K citations

Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1

Kimberly A. McAllister, K.M. Grogg, David W. Johnson et al. · Nature Genetics · 1994 · 1.5K citations · Full text

Endothelial Cell Pathobiology, Vascular Disease, Developmental Biology +10

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

Linheng Li, Ian D. Krantz, Yu Deng et al. · Nature Genetics · 1997 · 1.3K citations

Mendelian Disorder, Genetic Disorder, Genetics +7