Imidazo[1,2-a]quinoxalin-4-amines: A novel class of nonxanthine A1-adenosine receptor antagonists

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

Michael F. Jarvis, Richard Schulz, A. Hutchison et al. · Journal of Pharmacology and Experimental Therapeutics · 1989 · 547 citations

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4-Amino[1,2,4]triazolo[4,3-a]quinoxalines. A novel class of potent adenosine receptor antagonists and potential rapid-onset antidepressants

Reinhard Sarges, Harry Howard, Ronald G. Browne et al. · Journal of Medicinal Chemistry · 1990 · 408 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13

8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) ? a selective high affinity antagonist radioligand for A1 adenosine receptors

Martin J. Lohse, Karl‐Norbert Klotz, Jutta Lindenborn-Fotinos et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 1987 · 395 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

125I-4-aminobenzyl-5'-N-methylcarboxamidoadenosine, a high affinity radioligand for the rat A3 adenosine receptor.

Mark E. Olah, Carola Gallo‐Rodriguez, Kenneth A. Jacobson et al. · Molecular Pharmacology · 1994 · 179 citations · Full text

Medicine, Molecular Biology, Pharmacology +11