Validation of operant social motivation paradigms using <scp>BTBR</scp> T+tf/J and C57<scp>BL</scp>/6J inbred mouse strains

Abstract

The results of the conditioning paradigms suggest that the BTBR strain has an overall deficit in motivated behavior. Furthermore, the results of the open-field observations may suggest that social differences in the BTBR strain are anxiety induced.