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Association between genetic variants of reported candidate genes or regions and risk of cleft lip with or without cleft palate in the polish population

Adrianna Mostowska, Kamil K. Hozyasz, Piotr Wójcicki, Barbara Biedziak, Patrycja Paradowska, Paweł P. Jagodzińśki

Birth Defects Research Part A Clinical and Molecular Teratology · 2010 · 78 citations · 33 references

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Abstract

Our findings confirmed that genetic variants of IRF6 and the polymorphism located in the 8q24 gene desert are strongly involved in the etiology of facial clefts in the Polish population sample.

References

33

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

Shinji Kondo, Brian C. Schutte, Rebecca J. Richardson et al. · Nature Genetics · 2002 · 891 citations · Full text

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Interferon Regulatory Factor 6 ( <i>IRF6</i> ) Gene Variants and the Risk of Isolated Cleft Lip or Palate

Theresa M. Zucchero, Margaret E. Cooper, Brion S. Maher et al. · New England Journal of Medicine · 2004 · 581 citations · Full text

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

Stefanie Birnbaum, Kerstin U. Ludwig, Heiko Reutter et al. · Nature Genetics · 2009 · 475 citations

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Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

Nature Genetics · 2008 · 422 citations · Full text

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Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert

Maya Ghoussaini, Honglin Song, Thibaud Koessler et al. · JNCI Journal of the National Cancer Institute · 2008 · 325 citations · Full text

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