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Determination of unbound fraction of imatinib and N-desmethyl imatinib, validation of an UPLC–MS/MS assay and ultrafiltration method

Separation ScienceUnbound FractionN-desmethyl ImatinibMedicineBioanalysisMass SpectrometryGas ChromatographyPathologyAnalytical ChemistryToxicologyLiquid ChromatographyClinical ChemistryChromatographic AnalysisPharmacologyUltrafiltration MethodChromatographyWater AnalysisDrug Analysis