The effect of statins and fibrates on interferon-γ and interleukin-2 release in patients with primary type II dyslipidemia

Statins as a newly recognized type of immunomodulator

Brenda R. Kwak, Flore Mulhaupt, Samir Myit et al. · Nature Medicine · 2000 · 1.4K citations

Inflammation, Autoimmune Disease, Allergy +6

Activation of human aortic smooth-muscle cells is inhibited by PPARα but not by PPARγ activators

Bart Staels, Wolfgang Köenig, Régine Merval et al. · Nature · 1998 · 1.1K citations

Molecular Pharmacology, Muscle Physiology, Molecular Physiology +14

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

Sawsan Youssef, Olaf Stüve, Juan C. Patarroyo et al. · Nature · 2002 · 1.1K citations

Inflammation, Autoimmune Disease, Disease Mechanism +13

Simvastatin Reduces Expression of Cytokines Interleukin-6, Interleukin-8, and Monocyte Chemoattractant Protein-1 in Circulating Monocytes From Hypercholesterolemic Patients

Abdolreza Rezaie-Majd, Thomas Maca, Robert A. Bucek et al. · Arteriosclerosis Thrombosis and Vascular Biology · 2002 · 374 citations · Full text

Isoprenoids as mediators of the biological effects of statins

James K. Liao · Journal of Clinical Investigation · 2002 · 343 citations

Lipid Peroxidation, Hyperlipidemia, Cholesterol Reduction +16