Journal of Clinical Microbiology · 2005 · 55 citations · 8 references
Life SciencesInfectious DiseasesMicrobiologyAntimicrobial ResistanceDiagnostic MicrobiologyMedical MicrobiologyAntibacterial ResistanceAntibiotic ResistanceAntimicrobial Susceptibility TestingMycobacterial DiagnosticsTuberculosis DiagnosisTuberculosis Diagnostic TestingDeletion AnalysisDrug Resistance TestingGenomic Deletion DetectionMolecular Drug ResistanceMolecular Drug Susceptibility TestingMycobacterium Bovis DetectionPhenotypic Drug Susceptibility TestingTuberculosis Drug Resistance
Mycobacterium bovis is best identified by screening those isolates of the Mycobacterium tuberculosis complex that have any pyrazinamide (PZA) resistance, using a confirmatory test such as spoligotyping, biochemical testing, or genomic deletion analysis. The sensitivity for detection of M. bovis is lowered to 82% when only PZA-monoresistant isolates are screened.
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