Concepedia

FeCl<sub>3</sub>-promoted alkylation of indoles by enamides

Tianmin Niu, Lehao Huang, Tianxing Wu, Yuhong Zhang

Organic & Biomolecular Chemistry · 2010 · 38 citations · 56 references

DOI

Concepts

Abstract

An efficient iron-promoted alkylation of indoles with enamides has been accomplished under mild reaction conditions. The reaction proceeded with remarkable regioselectivity leading exclusively to substitution by indoles at α-position of enamides.

References

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, , +13