Thapsigargin-coated intraocular lenses inhibit human lens cell growth

Thapsigargin, a tumor promoter, discharges intracellular Ca2+ stores by specific inhibition of the endoplasmic reticulum Ca2(+)-ATPase.

Ole Thastrup, Peter J. Cullen, Bjørn K. Drøbak et al. · Proceedings of the National Academy of Sciences · 1990 · 3.3K citations

Life Sciences, Cell Biology, Pharmacology +15

Global data on blindness.

B Thylefors, A D Négrel, R Pararajasegaram et al. · PubMed · 1995 · 1.1K citations

Medicine, Ophthalmology, Vision Science +17

POSTERIOR CAPSULE OPACIFICATION

David J. McIntyre · Evidence-Based Eye Care · 1999 · 822 citations

Persistent intracellular calcium pool depletion by thapsigargin and its influence on cell growth.

Tarun Kanti Ghosh, Junhui Bian, Alison D. Short et al. · Journal of Biological Chemistry · 1991 · 205 citations · Full text

Life Sciences, Biochemistry, Cell Biology +15

A study of human lens cell growth in vitro. A model for posterior capsule opacification.

C. S. C. Liu, I. Michael Wormstone, G. Duncan et al. · PubMed · 1996 · 169 citations

Medicine, Ophthalmology, Surgery +17