Schistosoma mansoni: Antischistosomal activity of the four optical isomers and the two racemates of mefloquine on schistosomula and adult worms in vitro and in vivo

Reduced Susceptibility to Praziquantel among Naturally Occurring Kenyan Isolates of Schistosoma mansoni

Sandra D. Melman, Michelle L. Steinauer, Charles Cunningham et al. · PLoS neglected tropical diseases · 2009 · 456 citations · Full text

Life Sciences, Infectious Diseases, Microbiology +17

Pharmacological differences between the optical isomers of ibuprofen: evidence for metabolic inversion of the (—)-isomer

S. S. Adams, P. Bresloff, C. G. Mason · Journal of Pharmacy and Pharmacology · 1976 · 386 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Schistosoma mansoni: Defined system for stepwise transformation of cercaria to schistosomule in vitro

F. J. Ramalho-Pinto, G. Gazzinelli, R. E. Howells et al. · Experimental Parasitology · 1974 · 370 citations

Veterinary Medicine, Biology, Infectious Diseases +13

An Assessment of Drug-Haematin Binding as a Mechanism for Inhibition of Haematin Polymerisation by Quinoline Antimalarials

Arnulf Dorn, Sudha Rani Vippagunta, Hugues Matile et al. · Biochemical Pharmacology · 1998 · 348 citations

Medicine, Medicinal Chemistry, Pharmacology +12

Mefloquine—An Aminoalcohol with Promising Antischistosomal Properties in Mice

Jennifer Keiser, Jacques Chollet, Shu-Hua Xiao et al. · PLoS neglected tropical diseases · 2009 · 202 citations · Full text

Medicine, Infectious Diseases, Pharmacology +17