Effect of cyclooxygenase genotype and dietary fish oil on colonic eicosanoids in mice

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

Masanobu Oshima, Joseph Dinchuk, Stacia Kargman et al. · Cell · 1996 · 2.4K citations · Full text

Inflammation, Intestinal Polyposis, Medicine +9

Chemopreventive activity of celecoxib, a specific cyclooxygenase-2 inhibitor, against colon carcinogenesis.

Toshihiko Kawamori, Chinthalapally V. Rao, Karen Seibert et al. · PubMed · 1998 · 924 citations

Anti-inflammatory, Oncology, Colon Carcinogenesis +13

Differential effects of prostaglandin derived from ω-6 and ω-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion

Dilprit Bagga, Ling Wang, Robin Farias‐Eisner et al. · Proceedings of the National Academy of Sciences · 2003 · 628 citations

Exacerbation of inflammation-associated colonic injury in rat through inhibition of cyclooxygenase-2.

Brian K. Reuter, Samuel Asfaha, André G. Buret et al. · Journal of Clinical Investigation · 1996 · 423 citations · Full text

Chronic Inflammatory Diseases, Prostaglandin Synthesis, Gastrointestinal Pharmacology +16

Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products*

M. Wada, Cynthia J. DeLong, Yu Hong et al. · Journal of Biological Chemistry · 2007 · 399 citations · Full text