Loss of LIN9, a member of the DREAM complex, cooperates with SV40 large T antigen to induce genomic instability and anchorage-independent growth

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.4K citations · Full text

Education, Cell Biology, Molecular Biology +15

FoxM1 is required for execution of the mitotic programme and chromosome stability

Jamila Laoukili, Matthijs R. H. Kooistra, Alexandra Le Bras et al. · Nature Cell Biology · 2005 · 821 citations

Life Sciences, Cell Biology, Molecular Biology +13

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

Darren J. Baker, Karthik B. Jeganathan, J. Douglas Cameron et al. · Nature Genetics · 2004 · 726 citations

Veterinary Medicine, Genetics, Molecular Genetics +12

Evolutionarily Conserved Multisubunit RBL2/p130 and E2F4 Protein Complex Represses Human Cell Cycle-Dependent Genes in Quiescence

Larisa Litovchick, Subhashini Sadasivam, Laurence Florens et al. · Molecular Cell · 2007 · 407 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

E2F4 and E2F5 Play an Essential Role in Pocket Protein–Mediated G1 Control

Stefan Gaubatz, Geoffrey J. Lindeman, Seiichi Ishida et al. · Molecular Cell · 2000 · 306 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7