Journal of the American Chemical Society · 2005 · 112 citations · 12 references
Natural SciencesChemistryMedicinal ChemistryCatalysisDrug DiscoveryOrganic ChemistryBiomimetic SynthesisHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisBiomimetic Stereoselective SynthesisHeterocyclic Medicinal ChemistryNatural Product Total SynthesisPericyclic Stereochemistry
The total synthesis of naphthoquinone natural products isolated from the Bignoniaceae plant family is described. Pinnatal, isopinnatal, sterekunthals A and B, pyranokunthones A and B, and anthrakunthone have been prepared along the lines of a biosynthetic proposal involving pericyclic reactions as key steps. The first case of catalysis in oxa 6pi electrocyclizations is reported.
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Natural Products Active Against African Trypanosomes: A Step Towards New Drugs
Sara Hoet, Fred R. Opperdoes, Reto Brun et al. · ChemInform · 2004 · 136 citations
Aleksey V. Kurdyumov, Richard P. Hsung, Kirsten Ihlen et al. · Organic Letters · 2003 · 79 citations